Tombusvirus internal replication element (IRE)

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Tombusvirus internal replication element (IRE)
File:RF00510.jpg
Predicted secondary structure and sequence conservation of Tombus_IRE
Identifiers
SymbolTombus_IRE
RfamRF00510
Other data
RNA typeCis-reg
DomainViruses
SOSO:0000233
PDB structuresPDBe

In virology, the tombusvirus internal replication element (IRE) is a segment of RNA located within the region coding for p92 polymerase. This element is essential for viral replication; specifically, it is thought to be required at an early stage of replication, such as template recruitment and/or replicase complex assembly.[1]

Other non-coding RNA structures in Tombusvirus include the 3' UTR region IV[2] and 5' UTR.[3][4]

References

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