Talnetant

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Talnetant
File:Talnetant.png
Clinical data
ATC code
  • none
Identifiers
  • 3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC25H22N2O2
Molar mass382.463 g·mol−1
3D model (JSmol)
  • CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O
  • InChI=1S/C25H22N2O2/c1-2-20(17-11-5-3-6-12-17)27-25(29)22-19-15-9-10-16-21(19)26-23(24(22)28)18-13-7-4-8-14-18/h3-16,20,28H,2H2,1H3,(H,27,29) ☒N
  • Key:BIAVGWDGIJKWRM-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Talnetant (SB-223,412) is a neurokinin 3 receptor antagonist developed by GlaxoSmithKline, which is being researched for several functions (primarily treatment of irritable bowel syndrome, despite a 2007 study finding no statistically significant improvement in rectal hypersensitivity over placebo). Its use as a potential antipsychotic drug for the treatment of schizophrenia has also been discontinued.[1][2][3][4]

See also

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References

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