TPD52L1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Tumor protein D52 is a protein that in humans is encoded by the TPD52L1 gene.[1][2][3]
Function
[edit | edit source]This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined.[3]
Interactions
[edit | edit source]TPD52L1 has been shown to interact with TPD52L2[4] and TPD52.[4]
References
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Further reading
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