TAPS (buffer)

TAPS

File:TAPS.svg
Names
Preferred IUPAC name 3-{[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonic acid
Other names N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid
Identifiers
CAS Number	29915-38-6 checkY
3D model (JSmol)	Interactive image
ChemSpider	108495 ☒N
ECHA InfoCard
E number
PubChem CID	121591
UNII	Y5DC3IN066 checkY
CompTox Dashboard (EPA)	{{#property:P3117}}
InChI InChI=1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14) ☒N Key: YNLCVAQJIKOXER-UHFFFAOYSA-N ☒N InChI=1/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14) Key: YNLCVAQJIKOXER-UHFFFAOYAP
SMILES C(CNC(CO)(CO)CO)CS(=O)(=O)O
Properties
Chemical formula	C7H17NO6S
Molar mass	243.27 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ☒N verify (what is checkY☒N ?) Infobox references

TAPS ([tris(hydroxymethyl)methylamino]propanesulfonic acid) is a chemical compound commonly used to make buffer solutions.

It can bind divalent cations, including Co(II) and Ni(II).

TAPS is effective to make buffer solutions in the pH range 7.7–9.1, since it has a pK_a value of 8.44 (ionic strength I = 0, 25 °C).

The pH (and pK_a at I ≠ 0) of the buffer solution changes with concentration and temperature, and this effect may be predicted e.g. using online calculators.