TAF1B
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). TATA box-binding protein-associated factor RNA polymerase I subunit B is an enzyme that in humans is encoded by the TAF1B gene.[1][2]
Function
[edit | edit source]Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs.[2]
Interactions
[edit | edit source]TAF1B has been shown to interact with RRN3.[3]
References
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Further reading
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