Scriptaid

Scriptaid

File:Scriptaid structure.png
Clinical data
ATC code	none
Identifiers
IUPAC name 6-(1,3-Dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide
CAS Number	287383-59-9 checkY
PubChem CID	5186
ChemSpider	4998
UNII	EJQ8CD8BSV
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C18H18N2O4
Molar mass	326.352 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO
InChI InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9,24H,1-3,10-11H2,(H,19,21) Key:JTDYUFSDZATMKU-UHFFFAOYSA-N

Scriptaid is a drug which acts as a histone deacetylase inhibitor, and was one of the first compounds discovered via high-throughput screening that acts at this target. Scriptaid itself was never developed for medical applications, but led to the development of structurally related drugs such as vorinostat, which have been accepted into clinical use. Most early research using these compounds focused on their anti-cancer activity, but more recent research has found scriptaid to be useful in other applications such as cloning and research into regulation of metabolism.