STAP1
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Signal-transducing adaptor protein 1 is a protein that in humans is encoded by the STAP1 gene.[1][2][3]
Function
[edit | edit source]The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a positive feedback loop, increasing Tec activity. A mouse ortholog, stem cell adaptor protein 1, shares 83% identity with its human counterpart.[3]
Interactions
[edit | edit source]STAP1 has been shown to interact with C19orf2.[4]
References
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Further reading
[edit | edit source]- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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