SS18L1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). SS18-like protein 1 is a protein that in humans is encoded by the SS18L1 gene.[1]
Function
[edit | edit source]Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene is fused in-frame to the 3-prime end of the SSX1, SSX2, or SSX4 gene. The SS18L1 gene is homologous to SS18.[1]
Interactions
[edit | edit source]SS18L1 has been shown to interact with CREB-binding protein.[2] Biochemical pull down assays reveal SS18L1 to interact with several components of the human SWI/SNF chromatin remodeling complex.[3]
References
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Further reading
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