SPRY4
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Protein sprouty homolog 4 is a protein that in humans is encoded by the SPRY4 gene.[1][2]
Function
[edit | edit source]SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002).[2]
Interactions
[edit | edit source]SPRY4 has been shown to interact with TESK1.[3]
See also
[edit | edit source]References
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Further reading
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External links
[edit | edit source]- PDBe-KB provides an overview of all the structure information available in the PDB for Human Protein sprouty homolog 4 (SPRY4)
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