SF3A2
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Splicing factor 3A subunit 2 is a protein that in humans is encoded by the SF3A2 gene.[1][2][3]
Function
[edit | edit source]This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.[3]
Interactions
[edit | edit source]SF3A2 has been shown to interact with DDX46.[4]
References
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Further reading
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