SEC23IP
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). SEC23-interacting protein is a protein that in humans is encoded by the SEC23IP gene.[1][2]
COPII-coated vesicles are involved in protein transport from the Endoplasmic Reticulum to the Golgi Apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.[2]
References
[edit | edit source]Further reading
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