SB-705498

SB-705498
	File:SB-705498 structure.png
Identifiers
	IUPAC name 1-(2-bromophenyl)-3-[(3R)-1-[5-(trifluoromethyl)pyridin-2-yl]pyrrolidin-3-yl]urea;
CAS Number	501951-42-4;
PubChem CID	9910486;
DrugBank	DB11883;
ChemSpider	8086137;
UNII	T74V9O0Y2W;
ChEMBL	ChEMBL207433;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C17H16BrF3N4O
Molar mass	429.241 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CN(C[C@@H]1NC(=O)NC2=CC=CC=C2Br)C3=NC=C(C=C3)C(F)(F)F;
	InChI InChI=1S/C17H16BrF3N4O/c18-13-3-1-2-4-14(13)24-16(26)23-12-7-8-25(10-12)15-6-5-11(9-22-15)17(19,20)21/h1-6,9,12H,7-8,10H2,(H2,23,24,26)/t12-/m1/s1; Key:JYILLRHXRVTRSH-GFCCVEGCSA-N;

SB-705498 is a drug which acts as a potent and selective blocker of the TRPV1 ion channel.^[1]^[2] It has been evaluated in clinical trials for the treatment of rhinitis and chronic cough.^[3]^[4]^[5]

References

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This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.

Identifiers
File:SB-705498 structure.png
IUPAC name 1-(2-bromophenyl)-3-[(3R)-1-[5-(trifluoromethyl)pyridin-2-yl]pyrrolidin-3-yl]urea
CAS Number	501951-42-4
PubChem CID	9910486
DrugBank	DB11883
ChemSpider	8086137
UNII	T74V9O0Y2W
ChEMBL	ChEMBL207433
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₇H₁₆BrF₃N₄O
Molar mass	429.241 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CN(C[C@@H]1NC(=O)NC2=CC=CC=C2Br)C3=NC=C(C=C3)C(F)(F)F
InChI InChI=1S/C17H16BrF3N4O/c18-13-3-1-2-4-14(13)24-16(26)23-12-7-8-25(10-12)15-6-5-11(9-22-15)17(19,20)21/h1-6,9,12H,7-8,10H2,(H2,23,24,26)/t12-/m1/s1 Key:JYILLRHXRVTRSH-GFCCVEGCSA-N