Reversine

Reversine

Names
IUPAC name N′-Cyclohexyl-N-(4-morpholinophenyl)-7H-purine-2,6-diamine
Identifiers
CAS Number	656820-32-5 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:70723 N
ChemSpider	182286 N
ECHA InfoCard
E number
MeSH	C484369
PubChem CID	210332
UNII	Z499CLJ023 Y
CompTox Dashboard (EPA)	{{#property:P3117}}
InChI InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27) N Key: ZFLJHSQHILSNCM-UHFFFAOYSA-N N InChI=1/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27) Key: ZFLJHSQHILSNCM-UHFFFAOYAD
SMILES C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
Properties
Chemical formula	C21H27N7O
Molar mass	393.495 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation.

It also has the potential to selectively induce cell death in cancer cells.

Reversine is known to act as an antagonist of the adenosine A₃ receptor. Reversine is a potent inhibitor of the mitotic kinase Mps1 and it is widely used to study the process of chromosome segregation.