Proroxan
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| Clinical data | |
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| Other names | Pyrroxane, Pirroksan |
| Legal status | |
| Legal status |
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| Identifiers | |
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| CAS Number | |
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| KEGG | |
| E number | {{#property:P628}} |
| CompTox Dashboard (EPA) |
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| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C21H23NO3 |
| Molar mass | 337.419 g·mol−1 |
| 3D model (JSmol) | |
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Proroxan (INN; also known as pyrroxane and pirroksan) is a pharmaceutical drug used as an antihypertensive and in the treatment of Ménière's disease, motion sickness, and allergic dermatitis.[1][2]
Proroxan is a non-selective alpha-blocker (α-adrenoreceptor antagonist).[1]
Proroxan was developed in the 1970s at the Institute of Toxicology of the USSR Ministry of Health[3] and today is primarily used in Russia. Though originally developed as an antihypertensive, its use can lead to a decrease in alcohol and drug consumption. Currently proroxan is used almost exclusively in psychiatry, narcology, and neurology.[3]
References
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