Polysaccharide-K

Polysaccharide-K (Krestin, PSK) is a protein-bound polysaccharide isolated from the mycelium[1][2] of Trametes versicolor.
Although PSK is approved in Japan as an adjuvant therapy in cancer treatment,[3] it is not approved in the United States for treatment of cancer or any clinical condition.[4]
Research
[edit | edit source]There is little evidence that turkey tail mushroom extracts or PSK are useful for treating cancer or any medical condition.[4]
Polysaccharide-K, an extract of T. versicolor, is approved in Japan as an adjuvant therapy in cancer treatment.[3]
Chemistry
[edit | edit source]PSK is a protein polysaccharide consisting of a beta-glucan β-1,4 main chain with β-1,3 and β-1,6 side chains. The approximate molecular weight of PSK is 100,000 Da, and the protein component is reported at the β-1,6 side chain.[5] PSK is isolated from the "CM-101" strain of Trametes versicolor. The analogous compound PSP, is derived from the "COV-1" strain of Trametes versicolor.[6]
See also
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References
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