Pitofenone

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Pitofenone
Names
Preferred IUPAC name
Methyl 2-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}benzoate
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
E number Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).
UNII
  • {{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
  • InChI=1S/C22H25NO4/c1-26-22(25)20-8-4-3-7-19(20)21(24)17-9-11-18(12-10-17)27-16-15-23-13-5-2-6-14-23/h3-4,7-12H,2,5-6,13-16H2,1H3 N
    Key: NZHMAQSCHUSSSJ-UHFFFAOYSA-Nanalgesics N
  • InChI=1/C22H25NO4/c1-26-22(25)20-8-4-3-7-19(20)21(24)17-9-11-18(12-10-17)27-16-15-23-13-5-2-6-14-23/h3-4,7-12H,2,5-6,13-16H2,1H3
    Key: NZHMAQSCHUSSSJ-UHFFFAOYAG
  • COC(=O)C1=CC=CC=C1C(=O)C2=CC=C(C=C2)OCCN3CCCCC3
Properties
C22H25NO4
Molar mass 367.445 g·mol−1
Melting point 168-169 °C (Hydrochloride)[1]
Pharmacology
A03DA02 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Pitofenone is an antispasmodic.

Pitofenone is typically used in combination with fenpiverinium bromide, and metamizole sodium. Previously produced as Baralgin by Sanofi Aventis, the drug is currently sold in Eastern Europe under various trade names, including Spasmalgon (Actavis, Bulgaria), Revalgin (Shreya, India), Spasgan (Wockhardt, India), Bral (Micro Labs, India), and others.[2] It relieves pain and spasms of smooth muscles.[3]

References

[edit | edit source]
  1. ^ Entry on Pitofenon. at: Römpp Online. Georg Thieme Verlag, retrieved 22. Juni 2019.
  2. ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  3. ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).