Phyllodulcin

Phyllodulcin
	Chemical structure of hyllodulcinChemical structure of phyllodulcin
Names
	Preferred IUPAC name (3R)-8-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-1H-2-benzopyran-1-one
	Other names Praeruptorin
Identifiers
CAS Number	21499-23-0 check;
3D model (JSmol)	Interactive image;
ChemSpider	129391;
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E number	Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).
PubChem CID	146694;
UNII	9DDW04R41V check;
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	InChI InChI=1S/C16H14O5/c1-20-13-6-5-9(7-12(13)18)14-8-10-3-2-4-11(17)15(10)16(19)21-14/h2-7,14,17-18H,8H2,1H3/t14-/m1/s1 Key: PBILBHLAPJTJOT-CQSZACIVSA-N;
	SMILES COc1ccc(cc1O)[C@H]2Cc3cccc(c3C(=O)O2)O;
Properties
Chemical formula	C16H14O5
Molar mass	286.27 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). check verify (what is check☒ ?) Infobox references

Phyllodulcin is a dihydroisocoumarin found in Hydrangea macrophylla^[1] and Hydrangea serrata.^[2] It is a sweetener 400–800 times sweeter than sugar.^[3]

References

^ Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and Thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Matsuda H., Shimoda H., Yamahara J. and Yoshikawa M., Biological & pharmaceutical bulletin, 1999, vol. 22, no. 8, pp. 870–872, INIST 1959604.
^ Accumulation of phyllodulcin in sweet-leaf plants of Hydrangea serrata and its neutrality in the defence against a specialist leafmining herbivore. Mami Ujihara, Masateru Shinozaki and Makoto Kato, Researches on population ecology, Volume 37, Number 2, pp. 249–257, Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value)..
^ Chemical and Functional Properties of Food Saccharides. P. Tomasik, CRC Press, Boca Raton, 2003, Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value)..

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v t e Types of isocoumarins
Aglycones	Bergenon Thunberginol A and B
Dihydroisocoumarins	Hydrangenol Mellein 6-Hydroxymellein 6-Methoxymellein Monocerin Phyllodulcin Thunberginol C, D, E and G

v t e Artificial foods
Artificial fat substitutes	Olestra
Artificial protein substitutes	Acid-hydrolyzed vegetable protein
Artificial sugar substitutes	Acesulfame potassium Alitame Advantame Aspartame Aspartame-acesulfame salt Carrelame Dulcin Glucin Hydrogenated starch hydrolysates Lugduname Neohesperidin dihydrochalcone Neotame Saccharin Sodium cyclamate Sucralose
Natural food substitutes	Cheese analogues Coffee substitutes Egg substitutes Meat substitutes bacon list Milk substitutes Phyllodulcin Salt substitutes
Brands	Tang
Related topics	Food safety List of food additives

Names
Chemical structure of hyllodulcin Chemical structure of phyllodulcin
Preferred IUPAC name (3R)-8-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-1H-2-benzopyran-1-one
Other names Praeruptorin
Identifiers
CAS Number	21499-23-0^checkY
3D model (JSmol)	Interactive image
ChemSpider	129391
ECHA InfoCard	Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
E number	Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).
PubChem CID	146694
UNII	9DDW04R41V^checkY
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
InChI InChI=1S/C16H14O5/c1-20-13-6-5-9(7-12(13)18)14-8-10-3-2-4-11(17)15(10)16(19)21-14/h2-7,14,17-18H,8H2,1H3/t14-/m1/s1 Key: PBILBHLAPJTJOT-CQSZACIVSA-N
SMILES COc1ccc(cc1O)[C@H]2Cc3cccc(c3C(=O)O2)O
Properties
Chemical formula	C₁₆H₁₄O₅
Molar mass	286.27 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). checkY verify (what is ^checkY☒N ?) Infobox references