OSTbeta
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Organic solute transporter beta, also known as OST-beta, is a protein which in humans is encoded by the OSTB gene.[1][2]
Function
[edit | edit source]OST-beta together with OST-alpha is able to transport estrone sulfate, taurocholate, digoxin, and prostaglandin E2 across cell membranes.[2][3] The Ost-alpha / Ost-beta heterodimer, but not the individual subunits, stimulates sodium-independent bile acid uptake.[3] The heterodimer furthermore is essential for intestinal bile acid transport.[4]
OST-alpha and OST-beta have high expression in the testis, colon, liver, small intestine, kidney, ovary, and adrenal gland.[2]
See also
[edit | edit source]References
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Further reading
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