OR7D4
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Olfactory receptor 7D4 is a protein that in humans is encoded by the OR7D4 gene.[1][2][3][4][5][6][7]
Function
[edit | edit source]Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
Ligands
[edit | edit source]People with the OR7D4 R88W/T133M polymorphism are less sensitive to these odorants and find them less offensive smelling, as they are characteristically described as "sweaty".[4]
References
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- ^ OR7D4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
