Nirvanol

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Nirvanol
File:Nirvanol.svg
Clinical data
Other names5-Ethyl-5-phenylhydantoin
Routes of
administration		By mouth[1]
ATC code
  • None
Identifiers
  • 5-Ethyl-5-phenylimidazolidine-2,4-dione
CAS Number
PubChem CID
ChemSpider
UNII
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC11H12N2O2
Molar mass204.229 g·mol−1
3D model (JSmol)
  • CCC1(C(=O)NC(=O)N1)C2=CC=CC=C2
  • InChI=InChI=1S/C11H12N2O2/c1-2-11(8-6-4-3-5-7-8)9(14)12-10(15)13-11/h3-7H,2H2,1H3,(H2,12,13,14,15)
  • Key:UDTWZFJEMMUFLC-UHFFFAOYSA-N

Nirvanol, also known as ethylphenylhydantoin, is a derivative of hydantoin with anticonvulsant properties. Its 5-ethyl-5-phenyl substitution pattern is similar to that of phenobarbital.[2] It is useful in the treatment of chorea.[3]

Metabolism

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Metabolism of nirvanol is stereoselective, with the (S)- enantiomer undergoing roughly 14 times more hydroxylation at the 4 position of the phenyl group than the (R)-enantiomer.[4][5]

References

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