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Definition

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Measles is a highly contagious infectious disease, caused by the measles virus.[1][2] It is also known as rubeola.

File:Measles virus.JPG

vs Rubella and Roseola

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not to be confused with Rubella, (German measles) and roseola, which are different diseases, caused by unrelated viruses.[3]

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Onset of illness

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Symptoms usually develop 10–12 days after exposure to an infected person, and last 7–10 days.[4][5]

File:Measles timeline exposure to illness.gif

Initial symptoms

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Initial symptoms typically include, fever, often greater than 40 °C (104 °F), cough, runny nose, and inflamed eyes.[1][6]

File:Thermometer Fever 40.png

Koplik's spots

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Small white spots, known as Koplik's spots, may form inside the mouth, two or three days after the start of symptoms.[6]

File:Koplik spots, measles 2019.jpg

But the classic sign is a red (flat) rash, which usually starts on the face three to five days after the start of symptoms, and then spreads to the rest of the body.[6]

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Common complications

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About 7% of cases have complications, including diarrhea, middle ear infection, and pneumonia.[7]

File:Chest radiograph in influensa and H influenzae, posteroanterior, annotated.jpg

Less likely complications

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Less commonly, seizures, blindness, or inflammation of the brain, may occur.[4][7]

File:Hsv encephalitis.jpg

Measles is an airborne disease, which spreads very easily, through the coughs and sneezes of infected people.[4]

File:Sneeze.JPG

Other ways to spread disease

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It may also be spread through contact with saliva, or nasal secretions.[4]

File:A mother's kiss.jpg

Contagiousness

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It is so contagious that a single infected person will spread it to nine out of ten non-immune people who live with them.[7]

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Duration of contagiousness

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One reason is that it can be spread four days before a rash develops, and continue for four days after the start of the rash.[7]

File:Measles contagious period.png

Immunity

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Fortunately, most people do not get the disease more than once.[4]

File:Immunity graphic.png

Diagnosis

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Testing for the measles virus in suspected cases is important, for public health efforts.[7]

Prevention

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The measles vaccine is effective at preventing the disease, and is often delivered in combination with other vaccines.[4]

File:Bracing for a short, sharp jab.jpg

Vaccine effectiveness

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Vaccination resulted in a 75% decrease in deaths from measles between 2000, and 2013, with about 85% of children worldwide being currently vaccinated.[4]

File:Measles-vaccine-coverage-worldwide-vs-measles-cases-worldwide.png

Treatment

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Once a person has become infected, no specific treatment is available,[4] but supportive care may improve outcomes.[4]

File:Intravenous therapy 2007-SEP-13-Singapore.JPG

Supportive care

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This may include oral rehydration solution (slightly sweet and salty fluids), healthy food, and medications to control the fever.[4][5]

File:Paracetamol acetaminophen 500 mg pills crop.jpg

Antibiotics

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Antibiotics may be used, if a secondary bacterial infection such as bacterial pneumonia occurs.[4]

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Vitamin A

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Vitamin A supplementation is also recommended in the developing world.[4]

File:Vitamin A.gif

Epidemiology

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Measles affects about 20 million people of all ages per year,[1] primarily in the developing areas of Africa, and Asia.[4][8]

File:Measles world map - DALY - WHO2004.svg

Preventable deaths

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It is one of the leading vaccine-preventable disease causes of death.[9][10]

File:Measles in African Child.jpg

Decrease in deaths

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In 1980, 2.6 million people died of it,[4] but by 2014, global vaccination programs had reduced the number of deaths to 73,000.[11][12]

File:Evolution of number of measles reported cases between 1980 and 2015.png

Increase in 2017

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Rates of disease and deaths, however, increased in 2017 due to a decrease in immunization, and may be as high as 10% in people with malnutrition.[4]

File:US Measles Cases 2010-2018.png

Greatest risk

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Most of those who die from the infection are less than five years old.[4][13] The overall risk of death among those infected is about 0.2%.[7]

File:Rash of rubella on back (crop).JPG

References

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