Monalazone

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Monalazone
File:Monalazone.svg
Clinical data
Trade namesNaclobenz-Natrium, Spergisin, Speton
Other namesp-(Chlorosulfamoyl)benzoic acid
Routes of
administration
Vaginal
Drug classDisinfectant
ATC code
  • None
Identifiers
  • 4-(chlorosulfamoyl)benzoic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC7H6ClNO4S
Molar mass235.64 g·mol−1
3D model (JSmol)
  • C1=CC(=CC=C1C(=O)O)S(=O)(=O)NCl
  • InChI=1S/C7H6ClNO4S/c8-9-14(12,13)6-3-1-5(2-4-6)7(10)11/h1-4,9H,(H,10,11)
  • Key:WGHSWNHOFPGMKJ-UHFFFAOYSA-N

Monalazone, used as monalazone disodium (INNTooltip International Nonproprietary Name; the disodium salt) and sold under the brand names Naclobenz-Natrium, Spergisin, and Speton, is a vaginal disinfectant or antiseptic and spermicidal contraceptive.[1][2][3][4] It is a sulfonylbenzoic acid derivative and is closely related structurally to halazone.[2] The compound was synthesized in 1937.[1] A vaginal tablet combination of 0.125 mg estradiol benzoate and 10 mg monalazone was previously marketed under the brand name Malun 25.[5][3]

References

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