Microbicide Trials Network

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The Microbicide Trials Network (MTN, 2006–2021) was a United States government-funded research organization working in the field of microbicides for sexually transmitted diseases.[1][2] The MTN focused on research into microbicides which would prevent HIV infection. The MTN was a member of HANC. After its closure, partner organization HIV Prevention Trials Network took control of its projects.[2]

Research

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The MTN's notable research included various clinical trials.

The results of the CAPRISA 004 trial inspired the research of the MTN and the microbicide field.[3]

The Vaginal and Oral Interventions to Control the Epidemic (VOICE) found a vaginal gel containing an anti-HIV drug to be ineffective at preventing HIV transmission.[4]

The HOPE study tested dapivirine vaginal rings for HIV prevention in 1,456 study participants at 14 sites in Malawi, South Africa, Uganda and Zimbabwe.[5]

References

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