MicC RNA
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| MicC RNA | |
|---|---|
| File:RF00121.jpg Predicted secondary structure and sequence conservation of MicC | |
| Identifiers | |
| Symbol | MicC |
| Alt. Symbols | IS063 |
| Rfam | RF00121 |
| Other data | |
| RNA type | Gene; sRNA |
| Domain | Bacteria |
| SO | SO:0000655 |
| PDB structures | PDBe |
The MicC non-coding RNA (previously known as IS063 [1]) is located between the ompN and ydbK genes in E. coli. This Hfq-associated RNA is thought to be a regulator of the expression level of the OmpC porin protein, with a 5′ region of 22 nucleotides potentially forming an antisense interaction with the ompC mRNA. Along with MicF RNA this family may act in conjunction with EnvZ-OmpR two-component system to control the OmpF/OmpC protein ratio in response to a variety of environmental stimuli.[2] The expression of micC was shown to be increased in the presence of beta-lactam antibiotics.[3]
See also
[edit | edit source]References
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Further reading
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