Methadone intermediate

Methadone intermediate

File:Methadone Intermediate Structure.svg
Clinical data
Routes of administration	N/A
ATC code	none
Legal status
Legal status	AU: S9 (Prohibited substance) BR: Class A1 (Narcotic drugs) DE: Anlage II (Authorized trade only, not prescriptible) UN: Narcotic Schedule I
Identifiers
IUPAC name 4-cyano-2-dimethylamino-4,4-diphenylbutane
CAS Number	125-79-1
PubChem CID	31331
ChemSpider	29065
UNII	0GYB2HJA89
KEGG	C22686
E number	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C19H22N2
Molar mass	278.399 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(CC(C#N)(C1=CC=CC=C1)C2=CC=CC=C2)N(C)C
InChI InChI=1S/C19H22N2/c1-16(21(2)3)14-19(15-20,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-13,16H,14H2,1-3H3 Key:GJJQIGFCGLPOQK-UHFFFAOYSA-N

Methadone intermediate (pre-methadone, methadone nitrile, dimethylaminodiphenylbutanonitrile) is a methadone precursor scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9254. The 2014 annual manufacturing quota was 32 875 kilos. It is listed as a Schedule I drug in Canada, but is only significant as a precursor for methadone, as it does not have analgesic activity in its own right, though it does show some atropine-like activity.

See also

• Moramide intermediate
• Pethidine intermediate A
• Pethidine intermediate B (norpethidine)
• Pethidine intermediate C (pethidinic acid)