Menogaril

Menogaril

Names
Other names 7-O-Methylnogarol
Identifiers
CAS Number	71628-96-1 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1234391 N
ChemSpider	4450900 N
ECHA InfoCard
E number
PubChem CID	5288818
UNII	8JSV4O30HQ N
CompTox Dashboard (EPA)	{{#property:P3117}}
InChI InChI=1S/C28H31NO10/c1-27(36)8-10-6-11-16(21(32)15(10)14(9-27)37-5)22(33)17-13(30)7-12-24(18(17)20(11)31)38-26-23(34)19(29(3)4)25(35)28(12,2)39-26/h6-7,14,19,23,25-26,30,32,34-36H,8-9H2,1-5H3/t14-,19+,23+,25-,26-,27-,28-/m1/s1 N Key: LWYJUZBXGAFFLP-OCNCTQISSA-N N InChI=1/C28H31NO10/c1-27(36)8-10-6-11-16(21(32)15(10)14(9-27)37-5)22(33)17-13(30)7-12-24(18(17)20(11)31)38-26-23(34)19(29(3)4)25(35)28(12,2)39-26/h6-7,14,19,23,25-26,30,32,34-36H,8-9H2,1-5H3/t14-,19+,23+,25-,26-,27-,28-/m1/s1 Key: LWYJUZBXGAFFLP-OCNCTQISBR
SMILES CO[C@@H]1C[C@](C)(O)Cc2cc3c(c(O)c21)C(=O)c1c(O)cc2c(c1C3=O)O[C@@H]1O[C@@]2(C)[C@H](O)[C@@H](N(C)C)[C@@H]1O
Properties
Chemical formula	C28H31NO10
Molar mass	541.55 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Menogaril is an anthracycline analog of nogalamycin which was developed in late 1970s. It has even stronger anticancer activity, and less toxicity, than nogalamycin. However, its development for clinical use was cancelled due to only moderate success with relatively high incidence of serious toxicity (43-44% in non-Hodgkin's lymphoma patients).