Magnesium L-threonate

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Magnesium L-threonate
File:Magnesium threonate.png
Names
IUPAC name
Magnesium bis[(2R,3S)-2,3,4-trihydroxybutanoate]
Other names
MgT
Identifiers
3D model (JSmol)
ChemSpider
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  • InChI=1S/2C4H8O5.Mg/c2*5-1-2(6)3(7)4(8)9;/h2*2-3,5-7H,1H2,(H,8,9);/q;;+2/p-2/t2*2-,3+;/m00./s1 N
    Key: YVJOHOWNFPQSPP-BALCVSAKSA-L N
  • InChI=1/2C4H8O5.Mg/c2*5-1-2(6)3(7)4(8)9;/h2*2-3,5-7H,1H2,(H,8,9);/q;;+2/p-2/t2*2-,3+;/m00./s1
    Key: YVJOHOWNFPQSPP-HSLCKNDHBH
  • [O-]C([C@H](O)[C@@H](O)CO)=O.[O-]C([C@H](O)[C@@H](O)CO)=O.[Mg+2]
Properties
C8H14MgO10
Molar mass 294.495 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Magnesium L-threonate is a magnesium salt of L-threonic acid having the formula Mg(C4H7O5)2.[1]

Magnesium L-threonate is purported to cross the blood-brain barrier more readily than regular magnesium ions,[2] although no credible evidence proving the claim exists. No biological mechanism is proposed how magnesium ions would overcome the rapid physiological redistribution after reaching the brain, justifying targeted delivery.

Weak evidence shows that magnesium L-threonate improves cognitive function in healthy adults, although the trial did not compare its efficacy against conventional magnesium formulations.[2]

References

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