Mucin 5AC
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Mucin-5AC (MUC-5AC) is a protein that is encoded by the MUC5AC gene in humans.[1][2][3]
MUC-5AC is a large gel-forming glycoprotein. In the respiratory tract, it protects against infection by binding to inhaled pathogens, which are subsequently removed by mucociliary clearance. Overproduction of MUC-5AC can contribute to diseases such as asthma and chronic obstructive pulmonary disease,[4] and has also been associated with greater protection against influenza infection.[5]
Clinical relevance
[edit | edit source]This gene has been linked to mucus hypersecretion in the respiratory tract and is associated to chronic obstructive pulmonary disease (COPD).[6]
References
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External links
[edit | edit source]- PDBe-KB provides an overview of all the structure information available in the PDB for Human Mucin-5AC
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