M7GpppX diphosphatase

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M7GpppX diphosphatase
Identifiers
EC no.3.6.1.59
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

M7GpppX diphosphatase (EC 3.6.1.59, DcpS, m7GpppX pyrophosphatase, m7GpppN m7GMP phosphohydrolase) is an enzyme with systematic name m7G5'ppp5'N m7GMP phosphohydrolase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

(1) m7G5'ppp5'N(3'ppp5'N)n + H2O 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n
(2) 7-methylguanosine 5'-diphosphate + H2O 7-methylguanosine 5'-phosphate + phosphate

Decapping is a process in the control of eukaryotic mRNA degradation.

References

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