LSU rRNA
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 | This article is missing information about structure (universal). (December 2020) |
Large subunit ribosomal ribonucleic acid (LSU rRNA) is the largest of the two major RNA components of the ribosome. Associated with a number of ribosomal proteins, the LSU rRNA forms the large subunit of the ribosome. The LSU rRNA acts as a ribozyme, catalyzing peptide bond formation.
| LSU rRNA | |
|---|---|
| Identifiers | |
| Symbol | LSU |
| Rfam | CL00112 |
| Other data | |
| PDB structures | PDBe |
Characteristics
[edit | edit source]| Type | LSU rRNA size | Species | Length | Accession | Reference |
|---|---|---|---|---|---|
| Bacterial (Prokaryotic) | 23S | Escherichia coli | 2,905 nt | NR_076322.1 | [1] |
| Archaeal (Prokaryotic) | 23S | Halobacterium salinarum | 2,906 nt | NR_076247.1 | [2] |
| Eukaryotic | 5.8S & 28S | Homo sapiens | 157 + 5,025 nt | NR_145821.1; M11167.1 | [3][4] |
| Mitochondrial | 16S | Homo sapiens | 1,559 nt | NC_012920.1 | [5][6] |
| Plastid | 23S | Arabidopsis thaliana | 2,810 nt | NC_000932.1 | [7] |
Use in phylogenetics
[edit | edit source]LSU rRNA sequences are widely used for working out evolutionary relationships among organisms, since they are of ancient origin and are found in all known forms of life.
See also
[edit | edit source]- SSU rRNA: the small subunit ribosomal ribonucleic acid.
References
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- ^ Homo sapiens mitochondrion, complete genome. "Revised Cambridge Reference Sequence (rCRS): accession NC_012920", National Center for Biotechnology Information. Retrieved on 20 February 2017.
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