Isoorientin
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| Names | |
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| IUPAC name
6-(β-D-Glucopyranosyl)-3′,4′,5,7-tetrahydroxyflavone
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| Systematic IUPAC name
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-1-benzopyran-4-one | |
| Other names
Luteolin-6-C-glucoside
Homoorientin | |
| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value). |
| E number | Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value). |
| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C21H20O11 | |
| Molar mass | 448.380 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Isoorientin (homoorientin) is a flavone, a chemical flavonoid-like compound. It is the luteolin-6-C-glucoside.
Natural occurrence
[edit | edit source]Isoorientin can be isolated from the passion flower,[1] Vitex negundo,[2] Terminalia myriocarpa, the Açaí palm, and Swertia japonica.
Potential pharmacology
[edit | edit source]Isoorientin has been studied for its potential pharmacological activity.[3] Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycaemic component in Gentiana olivieri.[4] Studies also showed that isoorientin is a potential neuroprotective compound against Alzheimer's disease.[5]
Metabolism
[edit | edit source]See also
[edit | edit source]References
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- ^ Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay- directed fractionation techniques. Ekrem Sezik, Mustafa Aslan, Erdem Yesilada, Shigeru Ito, Life Sciences, 28 January 2005, Volume 76, Issue 11, Pages 1223–1238, Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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