Inositol pentakisphosphate
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3D model (JSmol)
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| 7685231 | |
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PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C6H17O21P5 | |
| Molar mass | 580.050 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Inositol pentakisphosphate (abbreviated IP5) is a molecule derived from inositol tetrakisphosphate by adding a phosphate group with the help of Inositol-polyphosphate multikinase (IPMK). It is believed to be one of the many second messengers in the inositol phosphate family. It "is implicated in a wide array of biological and pathophysiological responses, including tumorigenesis, invasion and metastasis, therefore specific inhibitors of the kinase may prove useful in cancer therapy."[2]
IP5 also plays a role in defense signaling in plants. It potentiates the interaction of the plant hormone JA-Ile by its receptor.[3][4]
References
[edit | edit source]- ^ Sigma Aldrich
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