ING5
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Inhibitor of growth protein 5 is a protein that in humans is encoded by the ING5 gene.[1][2]
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.[2]
Interactions
[edit | edit source]ING5 has been shown to interact with EP300[1] and P53.[1]
References
[edit | edit source]Further reading
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