IL1RAP
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Interleukin-1 receptor accessory protein is a protein that in humans is encoded by the IL1RAP gene.[1][2][3]
Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes an interleukin 1 receptor accessory protein. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble.[3]
Interactions
[edit | edit source]IL1RAP has been shown to interact with TOLLIP[4] and Interleukin 1 receptor, type I.[5]
References
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Further reading
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External links
[edit | edit source]- Overview of all the structural information available in the PDB for UniProt: Q9NPH3 (Human Interleukin-1 receptor accessory protein) at the PDBe-KB.
- Overview of all the structural information available in the PDB for UniProt: Q61730 (Mouse Interleukin-1 receptor accessory protein) at the PDBe-KB.
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