Hydrangea febrifuga
| Hydrangea febrifuga | |
|---|---|
| File:Dichroa febrifuga Glasgow.jpg | |
| Scientific classification Edit this classification | |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Asterids |
| Order: | Cornales |
| Family: | Hydrangeaceae |
| Genus: | Hydrangea |
| Species: | H. febrifuga
|
| Binomial name | |
| Hydrangea febrifuga (Lour.) Y.De Smet & Granados
| |
| Synonyms[1] | |
|
Synonymy
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Hydrangea febrifuga is a flowering plant in the family Hydrangeaceae. It is a subshrub or shrub native to central and southern China, Indochina, Malesia, and New Guinea.[1]
National names
[edit | edit source]- Chinese: Chinese: 常山; pinyin: Audio file "Chang2shan1.ogg" not found)
- Indonesian language: gigil, alternatively tataruman
- Sundanese: ramram
- Papua: Hom dong (ฮอมดง):
- Thai: Yai khlang yai (ยายคลังใหญ่), in Nakhon Sri Thammarat, Yai Krang (ยายกรัง) in the South, and Hom Kham (ฮอมคำ) in Lanna (Northern Thai).
Traditional Chinese medicine
[edit | edit source]Dichroa febrifuga is an important herb in traditional Chinese medicine, where it is considered one of the 50 fundamental herbs.[2] The alkaloids febrifugine and isofebrifugine are believed to be responsible for its antimalarial effects.[3] In traditional preparations, it is used in conjunction with other plants such as Glycyrrhiza glabra (licorice), Ziziphus jujuba and Zingiber officinale (ginger).[4]
Potential drug against autoimmune disease
[edit | edit source]Halofuginone, sold under the brand name Halocur, is a coccidiostat used in veterinary medicine. It is a synthetic halogenated derivative of febrifugine, a natural quinazolinone alkaloid which can be found in dichroa febrifuga.[5]
Halofuginone inhibits the development of T helper 17 cells, immune cells that play an important role in autoimmune disease, but it does not affect other kinds of T cells which are involved in normal immune function.[6] Halofuginone therefore has potential for the treatment of autoimmune disorders.[7]
References
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External links
[edit | edit source]
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- Hydrangeaceae
- Flora of North-Central China
- Flora of South-Central China
- Flora of Southeast China
- Flora of Indo-China
- Flora of Malesia
- Flora of New Guinea
- Flora of Taiwan
- Medicinal plants of Asia
- Plants used in traditional Chinese medicine
- Plants described in 1790
- Taxa named by João de Loureiro
- Cornales stubs
- Medicinal plant stubs