Haplogroup CT

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Haplogroup CT
Possible time of origin~70,000 BP,[1] ~100,000 BP,[2] or ~101,000 BP[3]
Possible place of originAfrica,[4][5][6][2] possibly Northeast Africa[7]
AncestorHaplogroup BT
DescendantsHaplogroup CF, Haplogroup DE
Defining mutationsP9.1, M168, M294, V9, V41, V54, V189, and V226

Haplogroup CT is a human Y chromosome haplogroup. CT has two basal branches, CF and DE. DE is divided into a predominantly Asia-distributed haplogroup D-CTS3946 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, Native American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations.

Distribution

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Men who carry the CT clade have Y chromosomes with the SNP mutation M168, along with P9.1 and M294. These mutations are present in all modern human male lineages except A and B-M60, which are both found almost exclusively in Africa.

The most recent common male line ancestor (TMRCA) of all CT men today probably predated the recent African origin of modern humans, a migration in which some of his descendants participated. He is therefore thought to have lived in Africa before this proposed migration.[1][5][4] In keeping with the concept of "Y-chromosomal Adam" given to the patrilineal ancestor of all living humans, CT-M168 has therefore also been referred to in popularized accounts as being the lineage of "Eurasian Adam" or "Out of Africa Adam"; because, along with many African Y-lineages, all non-African Y-lineages descend from it.[8][7][6]

No male in paragroup CT* has ever been discovered in modern populations. This means that all males carrying this haplogroup are also defined as being in one of the several major branch clades. All known surviving descendant lineages of CT are in one of two major subclades, CF and DE. In turn, DE is divided into a predominantly Asia-distributed haplogroup D-CTS3946 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, Native American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations.[6]

According to a 2024 study, macrohaplogroup CT spread in the Sinai Peninsula after early humans left Africa and migrated to the Middle East about 130 kya.[9]

Subclades

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Haplogroup CF is a subclade of haplogroup CT.

Haplogroup DE is a subclade of haplogroup CT.

Phylogenetic trees

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Haplogroup CT (M168/PF1416)

Sources

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See also

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Genetics

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Y-DNA C subclades

References

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  1. ^ a b Karafet et al. (2008) give "70,000", citing "68,500±6000 years" from Hammer and Zegura (2002). Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).. The split between CF and DE (which in the absence of a paragroup CT* is equivalent to the age of CT) has been dated to 70,000–75,000 years ago in Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans, Nature 505, 87–91 (02 January 2014)
  2. ^ a b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  3. ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  4. ^ a b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  5. ^ a b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  6. ^ a b c Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  7. ^ a b Darwinian Detectives: Revealing the Natural History of Genes and Genomes, by Norman A. Johnson, 2007, Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value)., Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  8. ^ Genes, Culture, and Human Evolution: A Synthesis, By Linda Stone, Paul F. Lurquin, 2007, Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value)., page 187
  9. ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  10. ^ Pereira et al. (2010), Linking the sub-Saharan and West Eurasian gene pools: maternal and paternal heritage of the Tuareg nomads from the African Sahel, European Journal of Human Genetics (2010) 18, 915–923; Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).