HHAT
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| hedgehog acyltransferase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | HHAT | ||||||
| Alt. symbols | FLJ10724, MART-2, MART2, GUP2 | ||||||
| NCBI gene | 55733 | ||||||
| HGNC | 18270 | ||||||
| OMIM | 605743 | ||||||
| RefSeq | NM_018194 | ||||||
| UniProt | Q5VTY9 | ||||||
| Other data | |||||||
| EC number | 2.3.1.- | ||||||
| Locus | Chr. 1 q32 | ||||||
| |||||||
Hedgehog acyltransferase (HHAT), also called skinny hedgehog homology in humans, is a human gene.[1][2]
The HHAT gene encodes an enzyme that catalyzes N-terminal palmitoylation of sonic hedgehog. Mutations in HHAT produce a phenotype that is similar to loss of hedgehog function. Finally the HHAT protein shares a short but significant sequence similarity to membrane-bound O-acyltransferases.[3]
References
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- ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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External links
[edit | edit source]- HHATL protein, human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
