HDAC10
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene.[1][2][3] HDAC10 is a class IIb HDAC. It specifically has selectivity for long, slender polyamines like N8-acetylspermidine. [4]
Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing enzymatic activities of histone acetyltransferases and histone deacetylases, such as HDAC10, determine the acetylation status of histone tails (Kao et al., 2002).[supplied by OMIM][3]
Interactions
[edit | edit source]HDAC10 has been shown to interact with Histone deacetylase 2[5] and Nuclear receptor co-repressor 2.[5]
See also
[edit | edit source]References
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Further reading
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External links
[edit | edit source]- HDAC10+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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