GZMB
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Granzyme B is a serine protease that in humans is encoded by the GZMB gene.[1] Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.
CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.[2]
See also
[edit | edit source]References
[edit | edit source]Further reading
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- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
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External links
[edit | edit source]- The MEROPS online database for peptidases and their inhibitors: S01.010[permanent dead link]
