GAD2
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Glutamate decarboxylase 2 is an enzyme that in humans is encoded by the GAD2 gene.[1]
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff-person syndrome.[2]
Interactions
[edit | edit source]GAD2 has been shown to interact with GAD1.[3]
See also
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
References
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