Formiminoglutamic acid

Formiminoglutamic acid
	File:Formiminoglutamic acid.svg
Names
	IUPAC name N-(aminomethylidene)-L-glutamic acid
	Other names FIGLU
Identifiers
CAS Number	816-90-0 check;
3D model (JSmol)	Interactive image;
ChemSpider	388370 ☒;
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E number	Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).
MeSH	Formiminoglutamic+acid
PubChem CID	909;
UNII	YV703N7VOG check;
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).;
	InChI InChI=1S/C6H10N2O4/c7-3-8-4(6(11)12)1-2-5(9)10/h3-4H,1-2H2,(H2,7,8)(H,9,10)(H,11,12) Key: NRXIKWMTVXPVEF-UHFFFAOYSA-N;
	SMILES C(CC(=O)O)C(C(=O)O)N=CN;
Properties
Chemical formula	C6H10N2O4
Molar mass	174.156 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ☒ verify (what is check☒ ?) Infobox references

Formiminoglutamic acid (FIGLU; conjugate base, formiminoglutamate) is an intermediate in the catabolism of L-histidine to L-glutamic acid. It thus is also a biomarker for intracellular levels of folate. The FIGLU test is used to identify vitamin B₁₂ deficiency, folate deficiency, and liver failure or liver disease.^[1]^[2] It is elevated with folate trapping, where it is accompanied by decreased methylmalonic acid, increased folate and a decrease in homocysteine.^[3]

References

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^ FIGLU+Test at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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