Fabrizio Chiti
Fabrizio Chiti | |
|---|---|
 Fabrizio Chiti in 2015 | |
| Born | 7 July 1971 Florence, Italy |
| Alma mater | Biological Sciences, University of Florence, Italy(E.N.S., 1995) |
| Known for | Protein aggregation and amyloid |
| Awards |
|
| Scientific career | |
| Fields | Biophysics, Biochemistry |
| Institutions | Department of Experimental and Clinical Biomedical Sciences, University of Florence |
| Doctoral advisor | Chris Dobson |
| Other academic advisors | Giampietro Ramponi, Chris Dobson |
| Website | www |
Fabrizio Chiti (born in Florence, 7 July 1971) is an Italian biochemist noted for his work on Protein aggregation and amyloid.[1]
Education
[edit | edit source]Chiti is a graduate in Biological Sciences of the University of Florence (Italy).[2] He attained a PhD degree (D.Phil) in Chemistry in 2000 at the University of Oxford in UK.[2] He then worked as a postdoctoral researcher at the University of Florence, Italy, with Giampietro Ramponi as a supervisor (2000–2002) and at the University of Cambridge, UK, under the supervision of Chris Dobson (2002).[2]
Research and career
[edit | edit source]He was appointed as an Associate (2002) and then Full Professor (2010) at the University of Florence in Biochemistry.[2] Chiti provided contributions in the field of misfolding and aggregation, particularly in the field of amyloid[1] He rationalized how amino acid mutations induce protein aggregation and edited an equation to predict the effect of mutations on the aggregation of an unfolded protein,[3][4] which led to a search by many investigators of algorithms with predictive power on essential aspects of protein aggregation. He also correlated the toxicities of abnormal protein oligomers with specific structural properties of them.[5] His 2006 review with Chris Dobson on protein misfolding, amyloid formation and human disease,[6] later updated as a new report,[7] is a reference paper in the field of amyloid and received, as of October 2019, more than four thousands citations in scientific publications.[1][8]
Awards and honors
[edit | edit source]- Election to EMBO Young Investigator program, European Molecular Biology Organization, 2005[9]
- Election to member of Academia Europaea, 2015[10]
- Jean-Francois LeFèvre Lecture, École supérieure de biotechnologie Strasbourg, 2003[11]
- Maria Teresa Messori Roncaglia ed Eugenio Mari Award, Accademia Nazionale dei Lincei, 2010[12]
References
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