FGF20
| fibroblast growth factor 20 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | FGF20 | ||||||
| NCBI gene | 26281 | ||||||
| HGNC | 3677 | ||||||
| OMIM | 605558 | ||||||
| RefSeq | NM_019851 | ||||||
| UniProt | Q9NP95 | ||||||
| Other data | |||||||
| Locus | Chr. 8 p22 | ||||||
| |||||||
Fibroblast growth factor 20 is a protein which in humans is encoded by the FGF20 gene.[1]
Function
[edit | edit source]The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development,[2] cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be expressed in normal brain, particularly the cerebellum. The rat homolog is preferentially expressed in the brain and able to enhance the survival of midbrain dopaminergic neurons in vitro.[3]
References
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
