Examples of in vitro transdifferentiation by initial epigenetic activation phase approach

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List:[1]

  • Human dermal fibroblasts → multilineage blood progenitors (Oct4 and cytokine treatment)[2]
  • Mouse dermal fibroblasts → polygonal hyaline chondrogenic cells (Klf4, c-Myc, Sox9)[3]
  • Mouse dermal fibroblasts → cardiomyocytes (Oct4, Sox2, Klf4, JI1 and Bmp4)[4]
  • Fibroblasts → neural stem/progenitor cells (Oct4, Sox2, c-Myc, Klf4)[5]

See also

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References

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