Draft:Gene Solutions

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Gene Solutions is a biotechnology company based in Ho Chi Minh City, Vietnam, that develops genetic testing services using next-generation sequencing.[1] Founded in 2017, it initially specialised in non-invasive prenatal testing (NIPT) and later expanded into cancer screening tests.[2][3]

The company was established by Nguyen Hoai Nghia (CEO), Nguyen Huu Nguyen, and Giang Hoa.[4] It has been described as the market leader in NIPT in Vietnam.[2][5]

Expansion

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Gene Solutions started with prenatal testing in Vietnam and later grew into other Southeast Asian markets.[3] It opened a diagnostics lab and branch in Singapore to serve as a regional centre, and formed partnerships in countries including Thailand, Indonesia, the Philippines, and Malaysia.[2][6]

Funding

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Mekong Capital invested $15 million in 2021 through its Mekong Enterprise Fund IV.[4] A follow-on Series B round in 2023 raised $21 million from the same fund to support oncology testing and regional growth.[5]

In November 2025, the company announced plans to raise up to $100 million through a pre-IPO round and a possible 2026 listing, potentially in Singapore or Hong Kong.[1]

Tests and research

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Its main prenatal test is triSure, a non-invasive screening for chromosomal abnormalities.[2]

For cancer detection, Gene Solutions offers SPOT-MAS, a multi-cancer early detection test based on circulating tumor DNA analysis.[5] The underlying technology, involving multimodal analysis of cell-free DNA methylation and fragmentomics, underwent analytical validation in a case-control study and was published in the journal eLife in 2023.[7]

Clinical validation of SPOT-MAS has been reported in several independent studies, including an interim report from a prospective cohort of nearly 2,800 participants published in Cancer Investigation (2023),[8] and results from the large-scale K-DETEK prospective trial (over 9,000 asymptomatic participants) published in BMC Medicine.[9]

References

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