Divaricatic acid

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Divaricatic acid
File:Divaricatic acid.svg
Names
IUPAC name
2-Hydroxy-4-(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy-6-propylbenzoic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
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  • InChI=1S/C21H24O7/c1-4-6-12-9-15(11-16(22)18(12)20(24)25)28-21(26)19-13(7-5-2)8-14(27-3)10-17(19)23/h8-11,22-23H,4-7H2,1-3H3,(H,24,25)
    Key: FSRDIJIAQPSMMR-UHFFFAOYSA-N
  • CCCC1=C(C(=CC(=C1)OC)O)C(=O)OC2=CC(=C(C(=C2)O)C(=O)O)CCC
Properties
C21H24O7
Molar mass 388.416 g·mol−1
Appearance Colorless crystalline needles
Melting point 129 °C (264 °F; 402 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Divaricatic acid is a chemical compound with the molecular formula C21H24O7. It is found in a variety of lichens, including some in the genera Evernia,[1] and Lepraria,[2] and Ramalina.[3] It is classified as a depside.

Divaricatic acid forms colorless crystalline needles with a melting point of 129 °C.[4]

Divaricatic acid has antibacterial properties against some Gram positive bacteria, such as Bacillus subtilis, Staphylococcus epidermidis, Streptococcus mutans, and Enterococcus faecium.[5] Since it also has activity against methicillin-resistant Staphylococcus aureus (MRSA) with a potency equivalent to that of vancomycin, it has been suggested as a potential treatment for MRSA.[5] It also has molluscicidal activity against Biomphalaria glabrata (ram's horn snail) and antiparasitic activity against cercariae of Schistosoma mansoni (blood fluke).[6]

References

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