Chlorophyllide a reductase

Chlorophyllide a reductase
Identifiers
EC no.	1.3.7.15
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Chlorophyllide a reductase (EC 1.3.7.15), also known as COR, is an enzyme with systematic name bacteriochlorophyllide-a:ferredoxin 7,8-oxidoreductase. It catalyses the following chemical reaction

chlorophyllide a + 2 reduced ferredoxin + ATP + H₂O + 2 H⁺ $\rightleftharpoons$ 3-deacetyl 3-vinylbacteriochlorophyllide a + 2 oxidized ferredoxin + ADP + phosphate

• Structure of the substrate and product of the enzyme
• Chlorophyllide a
  Chlorophyllide a
• Bacteriochlorophyllide a (R=H). The product of COR retains the vinyl group of the substrate in place of the acetyl group shown
  Bacteriochlorophyllide a (R=H). The product of COR retains the vinyl group of the substrate in place of the acetyl group shown

This reduction (with trans stereochemistry) of the pyrrole ring B gives the characteristic 18-electron aromatic system that distinguishes bacteriochlorophylls from chlorophylls, which retain the chlorin system of chlorophyllide a. This enzyme is present in purple bacteria such as Rhodobacter capsulatus and Rhodobacter sphaeroides, and Pseudomonadota. It is a component of the biosynthetic pathway to bacteriochlorophylls.

See also

• Biosynthesis of bacteriochlorophylls