Cephaeline
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| Names | |
|---|---|
| IUPAC name
7′,10,11-Trimethoxyemetan-6′-ol
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| Systematic IUPAC name
(1R)-1-{[(2S,3R,11bS)-3-Ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl]methyl}-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol | |
| Other names
Cepheline; Desmethylemetine; Dihydropsychotrine
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| Identifiers | |
3D model (JSmol)
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| ChEMBL | |
| ChemSpider | |
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| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C28H38N2O4 | |
| Molar mass | 466.622 g·mol−1 |
| Appearance | White silky crystals |
| Solubility in ethanol | Soluble[vague] |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
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Emetic / poisonous |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Cephaeline is an alkaloid that is found in Cephaelis ipecacuanha and other plant species including Psychotria acuminata.[1] Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac.[2] Chemically, it is closely related to emetine.
Poison treatment
[edit | edit source]Cephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness.[3]
References
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