CORO2A
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Coronin, actin binding protein, 2A is a protein that in humans is encoded by the CORO2A gene.[1]
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].[1]
References
[edit | edit source]External links
[edit | edit source]- Human CORO2A genome location and CORO2A gene details page in the UCSC Genome Browser.
Further reading
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