CLDN5
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Claudin-5 is a protein that in humans is encoded by the CLDN5 gene.[1][2][3] It belongs to the group of claudins.
Function
[edit | edit source]This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.[3]
Interactions
[edit | edit source]CLDN5 has been shown to interact with CLDN1[4] and CLDN3.[4]
References
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External links
[edit | edit source]- Human CLDN5 genome location and CLDN5 gene details page in the UCSC Genome Browser.
Further reading
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